Buy Xanax online (Alprazolam) is used for the purpose of treating anxiety and panic disorders. Alprazolam is the generic name and it is sold under the name Xanax. It is from a family of drugs called Benzodiazepines (anti-anxiety drugs) that in general produce calming effects in the brain. Xanax acts by slowing down the abnormal excitement in the brain. Xanax facilitates gamma-aminobutyric acid (GABA) in the brain to ease nervous tension. Other members of this family are clonazepam (Klonopin), diazepam (Valium), flurazepam (Dalmane) andlorazepam (Ativan),
SAFETY OF USE AND SIDE EFFECTS:
Xanax is approved by the FDA (Food and Drug Administration) in October 1981 after its short-term efficacy was proved intwolarge, randomized, clinical trials.Clinically acceptable tolerability versus placebo concentration range was found to be between 20 and 40 ng/mL that is effective in treating panic disorder. Any concentration higher than this was found to have more significant depressant effects on the CNS(central nervous system). The side effects of alprazolam are due to its excess pharmacological activity on the brain.The common side effects associated with Xanax are:
- Memory impairment
Various studies have found the withdrawal effects of Xanax if it is stopped after a long time. One way to prevent withdrawal symptoms is to take low doses of Xanax throughout the course of medication while another is to progressively decrease the dosage into smaller and smaller amounts with time instead of stopping it altogether. In comparison to other drugs of its family Xanax is considerably more toxic. Therefore, individuals at the risk of suicide and as well as those who are prune to substance addiction should avoid it because there is a risk of Xanax addiction due to its calming effects on the brain so care is needed in its use. In fact, long term use of Xanax is discouraged for everyone. Like all other benzodiazepines, tolerance can develop so that person would need to take more amount of drug to achieve same level of effects.
USE IN PREGNANCY:
Just like all other benzodiazepine, the use of alprazolam should be avoided during pregnancyparticularly in the first trimester. FDA has labelled Xanax as pregnancy category D, meaning that there is a risk of human fetal risk due to this medication during pregnancy.
Once inside the body Alprazolam is metabolized into hydroxy-alprazolam and 4-hydroxy-alprazolam through hepatic microsomal oxidation. Both of these metabolites have a lower affinity for the intrinsic benzodiazepine receptor as compared to alprazolam. Their concentration in the plasma is less than 10% of the total concentration of Alprazolam. 4-hydroxy-alprazolam has more concentration in the plasma but it is chemically less stable than hydroxy-alprazolam that’s why the concentration of alprazolam is more in urine. The chemical name of alprazolam is 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo [4,3-α] [1,4] benzodiazepine.
WHY BUY IT ONLINE?
Panic disorder and anxiety disorder are clinical conditions in which the patient needs proper medication to live their life comfortably. Pfizer Medical Information – US has provided a solution to this problem in the form of XANAX® tablets. In this global pandemic the incidence of anxiety and panic episodes is increasing so people suffering with these conditions should have access to XANAX® tablets all the time. But due to global lockdown and social distancing measures, it is not always safe to go outside to purchase Xanax, therefore, buy Xanax online is an ideal option for the people who rely on Xanax to manage their panic disorders and anxiety disorders. Buy Xanax online is often the better option in terms of time, money and convenience since Xanax does not require a prescription to buy it. So, buying Xanax online can save patients of panic disorders and anxiety disorders from a lot trouble.
- Ait-Daoud, N., Hamby, A. S., Sharma, S., & Blevins, D. (2018). A Review of Alprazolam Use, Misuse, and Withdrawal. Journal of Addiction Medicine, 12(1), 4–10. https://doi.org/10.1097/ADM.0000000000000350
- Alprazolam. (2021). In Wikipedia. https://en.wikipedia.org/w/index.php?title=Alprazolam&oldid=1017572086
- Alprazolam: MedlinePlus Drug Information. (n.d.). Retrieved April 20, 2021, from https://medlineplus.gov/druginfo/meds/a684001.html
- Greenblatt, D. J., & Wright, C. E. (1993). Clinical pharmacokinetics of alprazolam. Therapeutic implications. Clinical Pharmacokinetics, 24(6), 453–471. https://doi.org/10.2165/00003088-199324060-00003
- Greenfield, D. P., & Brown, J. A. (1994). What about Xanax? New Jersey Medicine: The Journal of the Medical Society of New Jersey, 91(6), 383–384.
- Hainsworth, A. (2012). Last night a Xanax saved my life. Australian Nursing Journal (July 1993), 20(1), 38.
- Huybrechts, I. (1991). The pharmacology of alprazolam: A review. Clinical Therapeutics, 13(1), 100–117.
- van Marwijk, H., Allick, G., Wegman, F., Bax, A., &Riphagen, I. I. (2012). Alprazolam for depression. The Cochrane Database of Systematic Reviews, 7, CD007139. https://doi.org/10.1002/14651858.CD007139.pub2
- Xanax (Alprazolam): Uses, Dosage, Side Effects, Interactions, Warning. (n.d.). RxList. Retrieved April 20, 2021, from https://www.rxlist.com/xanax-drug.htm
- Xanax (Alprazolam)—Side Effects, Interactions, Uses, Dosage, Warnings | Everyday Health. (n.d.). EverydayHealth.Com. Retrieved April 20, 2021, from https://www.everydayhealth.com/drugs/xanax
- Xanax Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing – WebMD. (n.d.). Retrieved April 20, 2021, from https://www.webmd.com/drugs/2/drug-9824/xanax-oral/details
Xanax XR for panic disorder. (2003). The Medical Letter on Drugs and Therapeutics, 45(1157), 43–44